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Whole blood-derived buffy coat products are rich in white blood cells and platelets and are a good source of cells for research applications. Each buffy coat is suspended in approximately 50 mL of plasma and contains approximately 2 X10(9) leukocytes/unit. The leukocyte populations in buffy coat products are very diverse. Units have from 35-80% granulocytes, 20-65% mononuclear cells, 7-24% CD3+, 4-20% CD4+, 2-11% CD8+, 1-6% NK Cells, .03-.09% CD34+, and 2-12% Monocytes.
Whole blood-derived buffy coat products are rich in white blood cells and platelets and are a good source of cells for research applications. Each buffy coat is suspended in approximately 50 mL of plasma and contains approximately 2 X10(9) leukocytes/unit. The leukocyte populations in buffy coat products are very diverse. Units have from 35-80% granulocytes, 20-65% mononuclear cells, 7-24% CD3+, 4-20% CD4+, 2-11% CD8+, 1-6% NK Cells, .03-.09% CD34+, and 2-12% Monocytes.